Lack of AKT in adipocytes causes severe lipodystrophy
Objective: Adipose depot mass is tightly regulated to maintain energy CALENDULA homeostasis.AKT is a critical kinase in the insulin-signaling cascade that is required for the process of adipogenesis in vitro.However, the role of AKT in the maintenance and/or function of mature adipocytes in vivo had not been examined.Methods: To study this, we dele